About Downtown Dermatology NYC

Established 2016
Led by Dr. Gilberto Alvarez del Manzano
Rated 4.9 Stars with over 270 reviews

At Downtown Dermatology, our mission is simple: provide exceptional skin care for every member of the family—children and adults alike—with compassion, expertise, and clarity. Centered in Manhattan’s Tribeca neighborhood, our board-certified dermatologists deliver the full spectrum of dermatologic services: medical, pediatric, cosmetic, and procedural.

Why Choose Us

Two highly skilled physicians, Dr. Alvarez and Dr. Karp, each bringing unique credentials and dedication to your skin health.
A warm, multilingual environment (English, Spanish, Portuguese) built to put patients—especially children—at ease.
Confidence in care: thorough skin evaluations, personalized treatment plans, and advanced technologies.
Seamless integration of medical and aesthetic dermatology, enabling holistic skin health under one roof.
Commitment to patient education and empowerment: we explain your options clearly and respect your preferences.

Our Team

Gilberto Alvarez Del Manzano, MD is dual-trained as an internist and dermatologist, serving both pediatric and adult patients. A Magna Cum Laude graduate and member of the Alpha Omega Alpha Honor Medical Society, he brings academic rigor and a gentle, attentive style.
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Anna Karp, MD is a board-certified dermatologist and Assistant Clinical Professor of Dermatology at NYU School of Medicine, specializing in both medical and cosmetic dermatology across all ages.

Our Services

Medical & Pediatric Dermatology: Conditions such as eczema, psoriasis, rashes, birthmarks, warts, and more. Our pediatric-friendly approach ensures children feel safe and supported.
Cosmetic Dermatology: Treatments ranging from wrinkle management and laser hair removal to advanced cosmetic procedures using the latest technology.
Skin Surgery & Cancer Care: Full-body skin exams, lesion removal, and skin cancer screenings performed with precision and care.

Our Philosophy

We believe skin health is foundational to well-being. We listen first—understanding your skin history, concerns, lifestyle—and then develop a treatment plan that aligns with your goals and values. Transparency, respect, and long-term support are at the heart of our practice.

Years of Trust and Outstanding Treatment

" I’ve been seeing Dr. Alvarez for many years for a variety of skin concerns. I look forward to my visits every time. But it’s more than just a good vibe (though there is that). I can speak freely, I feel heard, and I know that I have his full attention. He makes recommendations but without any sales pressure. His office staff has always been welcoming and helpful. I 100% recommend him. " -M.P.

" Dr. Karp is truly amazing! From the moment I walked in, I felt welcomed and at ease. She's incredibly knowledgeable and took the time to explain everything clearly, making me feel comfortable and confident in her care. I actually came to see her on a bit of a whim when my regular dermatologist couldn't get me in, but honestly, I won't be going back. Dr. Karp's exceptional care and welcoming demeanor have won me over completely. " - K.P.